Status of cellular immunity lacks prognostic significance in vulvar squamous carcinoma

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Status of cellular immunity lacks prognostic significance in vulvar squamous carcinoma.

OBJECTIVE It is generally recognized that the immune system has an important role in regulating cancer development. Evidence indicating a prognostic role of the immune system in vulvar carcinoma is scarce. This study investigated the presence and prognostic significance of several aspects of the immune system in vulvar squamous carcinoma. METHODS The number of intratumoral CD8(+) and Foxp3(+)...

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Clinical significance of galectin-7 in vulvar squamous cell carcinoma

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Objective(s) Matrix metalloproteinases comprise a family of enzyme that is able to degrade components of extra cellular matrix. There are single nucleotide polymorphisms in the promoter regions of several genes with ability to influence cancer susceptibility. The aim of this study was to analyses association between MMP2 and MMP9 promoter polymorphisms and head and neck squamous cell carcinoma...

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ژورنال

عنوان ژورنال: Gynecologic Oncology

سال: 2012

ISSN: 0090-8258

DOI: 10.1016/j.ygyno.2011.12.416